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<p><strong>Ibuprofen</strong> (INN) (<small><font size="2">IPA</font></small>: <span class="IPA" title="Pronunciation in IPA">/ˈaɪbjupɹofɛn/</span>) (from the earlier and no longer correct nomenclature <strong>i</strong>so-<strong>bu</strong>tyl-<strong>pro</strong>panoic-<strong>phen</strong>olic acid) is a non-steroidal anti-inflammatory drug (NSAID) originally marketed as <strong>Brufen</strong>, and since then under various other trademarks (see tradenames section), most notably Advil. It is used for relief of symptoms of arthritis, primary dysmenorrhea, fever, and as an analgesic, especially where there is an inflammatory component. Ibuprofen is known to have an antiplatelet effect, though it is relatively mild and short-lived when compared to that of aspirin or other more well-known antiplatelet drugs.</p>
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<h2p><span class="mw-headline"><font size="5">History</font></span></h2p>
<p>Ibuprofen was developed by the research arm of Boots Group during the 1960s<sup class="reference" id="cite_ref-0">[1]</sup>. It was discovered by Stewart Adams, with colleagues John Nicholson and Colin Burrows and was patented in 1961. The drug was launched as a treatment for rheumatoid arthritis in the United Kingdom in 1969, and in the United States in 1974. Dr Adams famously initially tested his drug on a hangover. He was subsequently awarded an OBE in 1987. Boots was awarded the Queen's Award For Technical Achievement for the development of the drug in 1987.<sup class="reference" id="cite_ref-title_Dr._Stewart_Adams:_I_tested_ibuprofen_on_my_hangover_-_Telegraph_1-0">[2]</sup></p>
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<h2><span class="mw-headline">External links</span></h2>
<ul>
<li>[http://drugome.org Drugome.org]: The ome of drugs.</li>
<li><a class="external text" title="http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682159.html" rel="nofollow" href="http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682159.html">U.S. National Library of Medicine: MedlinePlus Drug Information: Ibuprofen</a> </li>
<li><a class="external text" title="http://www.chm.bris.ac.uk/motm/ibuprofen/homepage.htm" rel="nofollow" href="http://www.chm.bris.ac.uk/motm/ibuprofen/homepage.htm">University of Bristol chemistry department page on Ibuprofen</a> </li>
