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<p><strong>Southern Blots vs Northern Blots</strong></p>
<p><strong>[[image:southern.gif]] [[image:northern.jpg]]<br />
<br /><br />DNA array = Massively parallel version of Southern &amp; Northern blotting&nbsp;<br /></strong>&nbsp;Difference <br />&nbsp;- &nbsp;Southern, Northern Blot<br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ; Distribute the oligonucleotide probes over a gel <br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Radioactively labeled oligonucleotide <br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &quot;one gene, one messenger &quot;<br />&nbsp;-&nbsp;DNA array<br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ; Oligonucleotide probes are immobilized on a surface&nbsp; at micrometer distance <br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Sample is usually labeled with a fluorescent dye <br />&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &quot; many genes, many messenger &quot;<br /><br /><br /></p>
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