<td bgcolor="#cccccc"><strong>&nbsp;Interleukin-4 Interferon alpha (ILIFN-4&alpha;) . </strong>1516-1927. B cell-stimulating factor &nbsp;Type 1 (BSF-1)interferon, leukocyte interferon, and lymphoblast interferon&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Mast cells, T cells, bone marrow stromal cells&nbsp;Lymphocytes and macrophages</td> <td bgcolor="#cccccc">&nbsp;Promotes growth Induces resistance to viruses and development inhibits cell proliferation. Regulates expression of B and T class ⅠMHC molecules on nucleated cells, and cells of the monocytic lineage. Also affects cells outside the immune system, including endothelial cells and fibroblasts.&nbsp;</td>

<td><strong>&nbsp;Interleukin-5 Interferon beta (ILIFN-5&beta;) . </strong>4520. Eosinophil differentiation factor (EDF)Type 1 interferon, eosinophil colony-stimulating factor (E-CSF)fibroblast interferon</td> <td>&nbsp;Mast Fibroblasts and some epithelial cells, T cells, eosinophils&nbsp;</td> <td>&nbsp;Induces eosinophil formation resistance to virus infection in target cells. Inhibits cell proliferation and differentiationregulates expression of class ⅠMHC molecules.&nbsp;</td>

<td bgcolor="#cccccc"><strong>&nbsp;Interleukin-6 Interferon gamma (ILIFN-6&gamma;) . </strong>26Monomer 17.1. Dimer 40. B cell stimulatory factor 2 (BSF-Type 2)interferon, hybridoma/plasmacytoma growth factor (HPGF)immune interferon, hepatocytemacrophage-stimulating activating factor (HSFMAF), and T cell interferon.</td> <td bgcolor="#cccccc">&nbsp;CD4+ and CD8+ T cells, B cells, several non-lymphoid cells including macrophages, bone marrow stromal NK cells, fibroblasts, endothelial cells, and astrocytes</td> <td bgcolor="#cccccc">&nbsp;Regulate Affects activation, growth, and differentiation of T cells, B cells, and T cell functions; in vivo effects macrophages, as well as NK cells. Upregulates MHC expression on hematopoiesis; inducer antigen-presenting cells. Signature cytokine of the acute phase responseTh1 differentiation. Weak anti-viral amd anti-proliferative activities.&nbsp;</td>

<td><strong>&nbsp;Interleukin-7 Leukemia inhibitory factor (IL-7LIF) . </strong>20-2845. Pre-BDifferentiation-cell growth inhibiting factor(DIA), lymphopoietindifferentiation-1 retarding factor (LP-1DRF)</td> <td>&nbsp;Bone marrow stromal Many cell types including T cells, thymic stromal cellsof the monocytic lineage, fibroblasts, liver, and spleen cells&nbsp;heart</td> <td>&nbsp;Growth factor for T Major experimental application: keeps cultures of ES cells in undifferentiated state to maintain their proliferation. In vivo, in combination with other cytokines, promotes hematopoiesis, stimulates acute phase response of liver cells, increases bone resorption, and B cell progenitorscauses loss of body fat.</td>

<td bgcolor="#cccccc"><strong>&nbsp;Interleukin-8 Macrophage colony stimulating factor (ILM-8CSF) . </strong>6Disulfide linked homodimer of 45-890. Neutrophil-attractant/activating protein Colony stimulating factor 1 (NAPCSF-1), neutrophil-activating factor (NAF), and granulocyte chemotactic protein (GCAP).</td> <td bgcolor="#cccccc">&nbsp;Many cell types including monocytes, lymphocytes, granulocytesmonocytes, and nonimmune system cells such as &nbsp;fibroblasts, endothelial cells, hepatocytes, and others&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Chemokine that cunctions primarily as a chemo-attractant Growth, differentiation, and activator of neutrophils; also attracts basophils survival factor for macrophage progenitors and some subpopulations of lymphocytes; has angiogenic activity.macrophages</td>

<td><strong>&nbsp;Interleukin-9 Macrophage inhibition factor (IL-9MIF) . </strong>32-39. P40; T cell growth factor Ⅲ12 monomer is biologically active in multimeric form.</td> <td>&nbsp;IL-2 Small amounts by many cell types; major producers are activated T helper cells, hepatocytes, and perhaps other cell populations&nbsp;types such as monocytes and epithelial cells</td> <td>&nbsp;Stimulates proliferation of T lymphocytes Activates macrophages and erythroid precursorsinhibits their migration.&nbsp;</td>

<td bgcolor="#cccccc"><strong>&nbsp;Interleukin-10 Oncostain M (IL-10OSM) . </strong>3528-4032. Onco M, ONC. Cytokine synthesis inhibitory factor (CSIF)</td> <td bgcolor="#cccccc">&nbsp;Activated subsets of CD4+ and CD8+ T cells&nbsp;and monocytes</td> <td bgcolor="#cccccc">&nbsp;Stimulates or enhances proliferation Many functions, including regulation of the growth and differentiation of B cellsduring hematopoiesis, thymocytesneurogenesis, and mast cells. In co-operation with TGF-&beta;, stimulates IgA synthesis and secretion by human B cells; antagonizes generation of the Th1 subset of helper T cells.osteogenesis</td>