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<td bgcolor="#cccccc"><strong> Interleukin-2 (IL-2) </strong>15-20. T cell growth factor (TCGF)</td>
<td bgcolor="#cccccc"> T cells </td>
<td bgcolor="#cccccc"> Stimulates growth and differentiation of T cells, B cells, and NK cells.</td>
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<td><strong> Interleukin-3 (IL-3) </strong>15.1(monomer), 30(dimer). Multi-colony-stimulating factor(M-CSF); hematopoietic cell growth factor (HCGF); mast cell growth factor (MCGF)<strong> </strong></td>
<td> Activated T cells, mast cells and eosinophils </td>
<td> Growth factor for hematopoietic cells and lymphocytes; stimulates colony formation in neutrophils, eosinophil, basophil, mast cell, erythroid, megakaryocyte, and monocytic lineages but not in lymphocytes. </td>
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<td bgcolor="#cccccc"><strong> Interleukin-4 (IL-4) </strong>15-19. B cell-stimulating factor 1 (BSF-1)</td>
<td bgcolor="#cccccc"> Mast cells, T cells, bone marrow stromal cells </td>
<td bgcolor="#cccccc"> Promotes growth and development of B and T cells, and cells of the monocytic lineage. Also affects cells outside the immune system, including endothelial cells and fibroblasts. </td>
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<td><strong> Interleukin-5 (IL-5) </strong>45. Eosinophil differentiation factor (EDF), eosinophil colony-stimulating factor (E-CSF)</td>
<td> Mast cells, T cells, eosinophils </td>
<td> Induces eosinophil formation and differentiation. </td>
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<td bgcolor="#cccccc"><strong> Interleukin-6 (IL-6) </strong>26. B cell stimulatory factor 2 (BSF-2), hybridoma/plasmacytoma growth factor (HPGF), hepatocyte-stimulating factor (HSF)</td>
<td bgcolor="#cccccc"> T cells, B cells, several non-lymphoid cells including macrophages, bone marrow stromal cells, fibroblasts, endothelial cells, and astrocytes</td>
<td bgcolor="#cccccc"> Regulate B and T cell functions; in vivo effects on hematopoiesis; inducer of the acute phase response. </td>
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<td><strong> Interleukin-7 (IL-7) </strong>20-28. Pre-B-cell growth factor, lymphopoietin-1 (LP-1)</td>
<td> Bone marrow stromal cells, thymic stromal cells, and spleen cells </td>
<td> Growth factor for T and B cell progenitors .</td>
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<td bgcolor="#cccccc"><strong> Interleukin-8 (IL-8) </strong>6-8. Neutrophil-attractant/activating protein (NAP-1), neutrophil-activating factor (NAF), and granulocyte chemotactic protein (GCAP).</td>
<td bgcolor="#cccccc"> Many cell types including monocytes, lymphocytes, granulocytes, and nonimmune system cells such as fibroblasts, endothelial cells, hepatocytes, and others </td>
<td bgcolor="#cccccc"> Chemokine that cunctions primarily as a chemo-attractant and activator of neutrophils; also attracts basophils and some subpopulations of lymphocytes; has angiogenic activity .</td>
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<td><strong> Interleukin-9 (IL-9) </strong>32-39. P40; T cell growth factor Ⅲ.</td>
<td> IL-2 activated T helper cell populations </td>
<td> Stimulates proliferation of T lymphocytes and erythroid precursors. </td>
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<td bgcolor="#cccccc"><strong> Interleukin-10 (IL-10) </strong>35-40. Cytokine synthesis inhibitory factor (CSIF)</td>
<td bgcolor="#cccccc"> Activated subsets of CD4+ and CD8+ T cells </td>
<td bgcolor="#cccccc"> Stimulates or enhances proliferation of B cells, thymocytes, and mast cells. In co-operation with TGF-β, stimulates IgA synthesis and secretion by human B cells; antagonizes generation of the Th1 subset of helper T cells.</td>
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<td><strong> Interleukin-11 (IL-11)</strong>23</td> <td> Bone marrow stromal cells and IL-1-stimulated fibroblasts </td> <td> Growth factor for plasmacytomas, megakaryocytes, amd macrophage progenitor cells. </td>
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<td><strong> Interleukin-12 (IL-12)</strong>Heterodimer containing a p35 subunit of 30-33, p40 subunit of 35-44. NK cells stimulatory factor (NKSF); cytotoxic lymphocyte maturation factor (CLMF)</td> <td> Macrophages and dendritic cells </td> <td> Important factor in inducing differentiation of Th1 subset helper T cells. Also induces interferon gamma production by T cells and NK cells and enhances NK cell activity. </td>
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<td><strong> Interleukin-13 (IL-13)</strong>17</td> <td> Activated T cells, mast cells, and NK cells </td> <td> Role in Th2 responses; upregulates synthesis of IgE and suppresses inflammatory responses. Involved in pathology of asthma and some allergic conditions. </td>
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<td><strong> Interleukin-14 (IL-14)</strong>60. High molecular weight B cell growth factor (HMW-BCGF)</td> <td> T cells </td> <td> Enhances B celss proliferation, inhibits antibody synthesis. </td>
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<td><strong> Interleukin-15 (IL-15)</strong>14-15</td> <td> Many cell types but primarily dendritic cells and cells of the monocytic lineage </td> <td> Stimulates T cell proliferation and development and activation of NK cells. </td>
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<td><strong> Interleukin-16 (IL-16)</strong>homotetramer 60; monomer ~17. Lymphocyte chemotatic factor (LCF)</td> <td> T cells </td> <td> Stomulates migration of CD4+ T cells, CD4+ monocytes, and eosinophils. Binding of IL-16 by CD4 inhibits HIV sinfection of CD4+ cells .</td>
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<td><strong> Interleukin-17 (IL-17)</strong>28-31. CTLA-8 (cytotoxic lymphocyte-associated antigen8)</td> <td> Primarily CD4+ T cells </td> <td> Supports hematopiesis indirectly by stimulating cytokine production by epithelial, endothelial, and fibroblastic stromal cells. Enhances expression of ICAM-1, thus making cells more adhesive. </td>
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