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<td><strong> CD63</strong></td>
<td> 16040-60</td> <td> αLIMP, MLA1, PTLGP40, gp55, granulophysin lysosomal-membrane-associated glycoprotein 3 (LAMP-2 integrin chain3), GPIa VLAmelanoma-2 α chainassociated antigen (ME491), neuroglandular antigen (NGA)</td> <td> B cellsPlatelets, monocytesendothelium, plateletsdegranulated neutrophils, megakaryocytes; neuronal, epithelialmonocytes, and endothelial cells; osteoclastsmacrophages endothelium</td> <td> Integrin that associates with CD29, binds collagen, laminin-1Not known</td>
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<td bgcolor="#cccccc"><strong> CD64</strong></td>
<td bgcolor="#cccccc"> 125, 30 72</td> <td bgcolor="#cccccc"> Fc&alphagamma;-3 integrin chain\RI, VLA-3 α chainFCRI</td> <td bgcolor="#cccccc"> B Monocytes, macrophages, bood and germinal-center dendritic cells, many adherent PMN activated by IFN-γ or G-CSF, early myeloid-lineage cells</td> <td bgcolor="#cccccc"> Integrin that associates with CD29, binds collagen, lamininPhagocytosis: receptor-mediated endocytosis of IgG-antigen complexes; antigen capture for presentation to T cells; antibody-5, fibronectin, entacin, invasindependent cellular cytotoxicity; mediator of release by some cells of cytokines and reactive oxygen intermediates</td>
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<td><strong> CD65</strong></td>
<td> 145</td> <td> αCeramide-4 integrin chaindodecasaccharide, VLAVIM-4 2; glycolipid&alphanbsp; chain</td> <td> Many cell types, including T cells, B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, dendritic Myeloid cells not on neutrophils</td> <td> Cell adhesion molecule for attachment to cell syrface ligands VCAM-1 (Not knownα4β1 and α4β7) and MAdCAM-1(α4β7) and attachment to extracellular matrix proteins fibronectin (α4β1 and α4β7) and thrombospondin (α4β1), and for lymphocyte migration and homingnbsp; co-stimulatory molecule for T-cell activation</td>
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<td bgcolor="#cccccc"><strong> CD65s</strong></td>
<td bgcolor="#cccccc"> 135</td> <td bgcolor="#cccccc"> αSialylated-5 integrin chainCD65, FNR &alphaVIM-2; chain, VLA-5 carbohydrate&alphanbsp; chain</td> <td bgcolor="#cccccc"> Many cell types, including memory T cellsGranulocytes, monocytes, platelets</td> <td bgcolor="#cccccc"> Integrin that associates Possible involvement with CD29, binds fibronectin, invasinphagocytosis and Ca 2+ influx </td>
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<td><strong> CD66a</strong></td>
<td> 125, 25160-180</td> <td> αNCA-6 integrinchain, platelet gpI160, VLA-6 biliary glycoprotein (BGP)&alphanbsp; chain</td> <td> T Granulocytes, epithelial cells, monocytes, platelets, megakaryocytes, trophoblasts</td> <td> Integrin that associates with CD29, binds laminin, invasin, merosineAdhesion molecule; receptor for <em>Neisseria gonorrheae</em> and <em>N. meningitidis</em>; trigger of neutrophil activation </td>
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<td bgcolor="#cccccc"><strong> CD66b</strong></td>
<td bgcolor="#cccccc">130 95-100</td> <td bgcolor="#cccccc"> Intercellular molecule-3CD67, CGM6, ICAMNCA-395 </td> <td bgcolor="#cccccc"> Leukocytes of all lineagesGranulocytes</td> <td bgcolor="#cccccc"> Co-stimulatory Adhesion molecule in immune response; regulator trigger of LFA-1/ICAM-1 and integrin-neutrophil activation&betanbsp;-dependent adhesion</td>
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<td><strong> CD66c</strong></td>
<td> 12590</td> <td> VNR-α chain, α V integrin chainNCA, vitronsctin receptor; forms αNCA-V integrin by association with CD6150/90 </td> <td> PlateletsGranulocytes, megakaryocytesepithelial cells </td> <td> Subunit Adhesion molecule; trigger of neutrophil activation&alphanbsp;-V integrin, which binds vitronsctin, von Willebrand factor, fibronectin, thrombospondin, and probably apoptotic cells</td>
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<td bgcolor="#cccccc"><strong> CD66d</strong></td>
<td bgcolor="#cccccc"> 25-2930</td> <td bgcolor="#cccccc"> CAMPATH-1, HE5CGM1 </td> <td bgcolor="#cccccc"> Thymocytes, lymphocytes, monocytes, macrophages, epithelial cells lining male reproductive tractGranulocytes</td> <td bgcolor="#cccccc"> Not knownUnclear; receptor for <em>Neisseria gonorrheae and N. meningitidis</em></td>
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<td><strong> CD66e</strong></td>
<td> 32180-42200</td> <td> MRC OX44Carcinoembryonic antigen (CEA) </td> <td> Leukocytes Epithelial cells</td> <td> Signal transductionUnclear; possible adhesion molecule crosslinking promotes activation of human B cells</td>
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<td bgcolor="#cccccc"><strong> CD66f</strong></td>
<td bgcolor="#cccccc"> 90, 7554-11572</td> <td bgcolor="#cccccc"> Intercellular adhesion moleculePregnancy-specific b1 glycoprotein, SP-1 , pregnancy-specific glycoprotein (ICAM-1PSG) </td> <td bgcolor="#cccccc"> Activated endothelial cells, activated T cells, activated B cells, monocytes, endothelial cellsFetal liver; produced in placenta and released </td> <td bgcolor="#cccccc"> Ligand for CD11a/CD18 or CD11b/CD18Unclear; receptor for rhinoviruses possible involvement in immune regulation and protection of fetus from maternal immune system; necessary for RBCs infected with malarial parasitessuccessful pregnancy </td>
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<td><strong> CD68</strong></td>
<td> 70, 55110</td> <td> Decay accelerating factor (DAF)gp110, macrosialin </td> <td> Most Monocytes, macrophages, dendritic cells, neutrophils, basophils, mast cells, myeloid progenitor cells, subset of CD34+ hematopoeitic progenitor cells, activated T cells, some peropheral-blood B cells </td> <td> Protective barrier against inappropriate complement activation and deposition on plasma membranesNot known </td>
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<td bgcolor="#cccccc"><strong> CD69</strong></td>
<td bgcolor="#cccccc"> 175-22060</td> <td bgcolor="#cccccc"> LeuActivation-19inducer molecule (AIM), EA1, MLR3, NKH1gp34/28, neural cell adhesion molecule very early activation (NCAMVEA) </td> <td bgcolor="#cccccc">Human Activated leukocytes, inducing T cells, thymocytes, B cells, NK celllscells, neutrophils, eosinophils, a and Langerhans cells; subset of mature thymocytes, germinal-center mantle B cells, some CD4+ and CD8+ germinal-center T cells </td> <td bgcolor="#cccccc"> Not known for the immune systemInvolvement in early events of lymphocyte, monocyte, and platelet activation: promotes Ca2+ influx, synthesis of cytokines and their receptors, induction of c-myc and c-fos proto-oncogene expression; adhesion molecule for role in promoting lysis mediated by activated NK cells of the nervous system </td>
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<td><strong> CD70</strong></td>
<td> 75, 95, 170 </td> <td> HNKCD27-1ligand, Leu-7; a carbohydrate Ki24 antigen (oligosaccharide), component of many glycoproteins </td> <td> NK cells; subsets of Activated T cells, and B cells, and monocytesmacrophages </td> <td> Not knownLigand for CD27; possible role in co-stimulation of B and T cells </td>
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<td bgcolor="#cccccc"> <strong>CD71</strong></td>
<td bgcolor="#cccccc"> 55-70190</td> <td bgcolor="#cccccc"> Lymphocyte function-associated antigen 3 (LFA-3)T9, transferrin receptor </td> <td bgcolor="#cccccc"> Many hematopoeitic and non-hematopoeitic celltypesAll proliferating cells </td> <td bgcolor="#cccccc"> Adhesion between killer T cells Iron uptake: binds ferrotransferrin at neutral pH and target ecllsinternalizes complex to acidic endosomal compartment, antigen-presenting cells and T cells, or thymocytes and thymic epithelial cellswhere tron is released </td>
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<td><strong> CD72</strong></td>
<td> 18-2542</td> <td> IFLy-5Ag19.2, H19, HRF20, MACIFLy-32.2, MIRL, PLyb-18 protectin 2</td> <td> B cells (except plasma cells) Many hematopoeitic and non-hematopoeitic celltypes </td> <td> Inhibitor for mrmbrane attack complex (MAC) assembly, thus protecting cells from complement mediated lysis; signaling role (as a GPI-anchored molecule) in T-cell activationNot known possible role in cell adhesion</td>
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<td bgcolor="#cccccc"><strong> CD73</strong></td>
<td bgcolor="#cccccc"> 69, 70, 72</td> <td bgcolor="#cccccc"> 9Ecto-O-acetyl-GD35', nucleotidase carbohydrate modification found on some gangliosides</td> <td bgcolor="#cccccc"> Subset Subpopulations of T and B cells, plateletsmany peripheral-blood B cells, thymic epitheliumfollicular dendritic cells, activated keratinocytesepithelial cells, synovial fibroblasts, glomeruli, smooth muscle endothelial cells, astrocytes </td> <td bgcolor="#cccccc"> Possible contributor Dephosphorylation of purine and pyrimidine ribo-and deoxyribonucleoside monophosphates to co-stimulatory/comitogenic signals for T cellstheir corresponding nucleosides </td>
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<td bgcolor="#cccccc"><strong> CD74</strong></td> <td bgcolor="#cccccc"> 33, 35, 41</td> <td bgcolor="#cccccc"> Class Ⅱ-specific chaperone, Li, invariant chain</td> <td bgcolor="#cccccc"> B cells, activated T cells, macrophages, activated endothelial and epithelial cells </td> <td bgcolor="#cccccc"> Intracellular sorting of MHC class Ⅱ molecules </td>
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<td bgcolor="#cccccc"> </td>
<td bgcolor="#cccccc"> </td>
<td bgcolor="#cccccc"> B cells, Subpopulation of peripheral-blood T cells, erythrocytes</td> <td bgcolor="#cccccc"> Cell adhesion; ligand for CD22 </td>
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