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CD46-60

119 bytes removed, 13:19, 6 September 2006
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<td><strong>&nbsp;CD51</strong></td>
<td>&nbsp;&alpha;&beta; dimer: &alpha;, 125; &beta;, 122&nbsp;</td> <td>&nbsp;GlycoproteinⅡb (GPⅡb) VNR-&alpha;Ⅱbchain, &nbspalpha;V integrin chain, vitronsctin receptor; forms platelet fibrinogen receptor &alpha;-V integrin by association with GP ⅢaCD61&nbsp;</td> <td>&nbsp;&nbsp;Platelets, megakaryocytes</td> <td>&nbsp;Subunit of platelet fibrinogen receptor&alpha;-V integrin, which mediates platelet aggregation by acting as receptor for fibrinogen; possibly also receptor for binds vitronsctin, von Willebrand factor, fibronectin, thrombospondin, and thrombospondin&nbsp;probably apoptotic cells</td>
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<td bgcolor="#cccccc"><strong>&nbsp;CD52</strong></td>
<td bgcolor="#cccccc">&nbsp;a, 23;&nbsp;<br /> &nbsp;b, 135,23;&nbsp;<br /> &nbsp;c, 22;25-29</td> <td bgcolor="#cccccc">&nbsp;a, GPIX; b, GPIbCAMPATH-&alpha;; c1, GPIb-&beta;; d, GPVHE5</td> <td bgcolor="#cccccc">&nbsp;PlateletsThymocytes, lymphocytes, monocytes, megakaryocytes&nbsp;macrophages, epithelial cells lining male reproductive tract</td> <td bgcolor="#cccccc">&nbsp;Adhesion of platelets to endothelium; amplification of platelet response to thrombin&nbsp;Not known</td>
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<td><strong>&nbsp;CD53</strong></td>
<td>&nbsp;9532-115 in&nbsp;<br /> T cells, 115-135 in neutrophils42</td> <td>&nbsp;gpL115, leukocyte sialoglycoprotein, leukosialin, sialophorin&nbsp;MRC OX44</td> <td>&nbsp;All leukocytes except most resting B cells&nbsp;Leukocytes </td> <td>&nbsp;Possible anti-adhesive (&quotSignal transduction;barrier&quot;) molecule mediating repulsion between leukocytes and other crosslinking promotes activation of human B cells&nbsp;</td>
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<td bgcolor="#cccccc"><strong>&nbsp;CD54</strong></td>
<td bgcolor="#cccccc">&nbsp;8590, 75-115</td> <td bgcolor="#cccccc">&nbsp;ECMR&nbsp;Ⅲ, H-CAM, HUTCHIntercellular adhesion molecule-1, Hermes, Lu, Pgp(ICAM-1, gp85&nbsp;)</td> <td bgcolor="#cccccc">&nbsp;Surface of most cell types&nbsp;Activated endothelial cells, activated T cells, activated B cells, monocytes, endothelial cells</td> <td bgcolor="#cccccc">&nbsp;Adhesion molecule mediating leukocyte attachment Ligand for CD11a/CD18 or CD11b/CD18; receptor for rhinoviruses and homing to peripheral lymphoid organs and sites of inflammation&nbsp;for RBCs infected with malarial parasites</td>
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<td><strong>&nbsp;CD55</strong></td>
<td>&nbsp;85-250 in epithelial cells; 85-200 in lymphocytes70, 55</td> <td>&nbsp;CD44v, CD44v9; heterogenous group of CD44 variant isoforms designated by the variant exons that they&nbsp;include Decay accelerating factor (v2-v10 in humansDAF)&nbsp;</td> <td>&nbsp;Epithelial Most cells and monocytes (constitutively), activated leukocytes&nbsp;</td> <td>&nbsp;Possible role (particulary for CD44v6) in leukocyte attachment to Protective barrier against inappropriate complement activation and rolling deposition on endothelial cells, homing to peripheral lymphoid organs and sites of inflammation&nbsp;plasma membranes</td>
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<td bgcolor="#cccccc"><strong>&nbsp;CD56</strong></td>
<td bgcolor="#cccccc">&nbsp;210, 175-220, 180, 200</td> <td bgcolor="#cccccc">&nbsp;Leukocyte common antigen Leu-19, NKH1, neural cell adhesion molecule (LCANCAM), T200, EC 3.1.3.4; many dofferent isoforms with different molecular weights, e.g..<br /> B220, CD45R, CD45RA, CD45RB, CD45RC, CD45RO&nbsp;</td> <td bgcolor="#cccccc">&nbsp;All hematopoeitic cells; different isoforms characteristic Human NK cellls, a subset of differentiated subsets of various hematopoeitic CD4+ and CD8+ T cells</td> <td bgcolor="#cccccc">&nbsp;Essential role in T-and B-cell antigen-receptor-mediated activation; possible role in receptor-mediated activation in other leukocytes&nbspNot known for the immune system;adhesion molecule for cells of the nervous system</td>
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<td bgcolor="#cccccc"><strong>&nbsp;CD57</strong></td> <td bgcolor="#cccccc">&nbsp;</td> <td bgcolor="#cccccc">&nbsp;HNK-1, Leu-7; a carbohydrate antigen (oligosaccharide), component of many glycoproteins&nbsp;</td> <td bgcolor="#cccccc">&nbsp;NK cells; subsets of T cells, B cells, and monocytes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Not known&nbsp;</td>
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<td bgcolor="#cccccc">&nbsp;<strong>CD58</strong></td>
<td bgcolor="#cccccc">&nbsp;55-70</td> <td bgcolor="#cccccc">&nbsp;Lymphocyte function-associated antigen 3 (LFA-3)&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Many hematopoeitic and non-hematopoeitic celltypes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Adhesion between killer T cells and target eclls, antigen-presenting cells and T cells, or thymocytes and thymic epithelial cells&nbsp;</td>
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<td bgcolor="#cccccc"><strong>&nbsp;CD59</strong></td> <td bgcolor="#cccccc">&nbsp;18-25</td> <td bgcolor="#cccccc">&nbsp;IF-5Ag, H19, HRF20, MACIF, MIRL, P-18 protectin&nbsp;</td> <td bgcolor="#cccccc">&nbsp;&nbsp;Many hematopoeitic and non-hematopoeitic celltypes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Inhibitor for mrmbrane attack complex (MAC) assembly, thus protecting cells from complement mediated lysis; signaling role (as a GPI-anchored molecule) in T-cell activation; possible role in cell adhesion</td>
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<td bgcolor="#cccccc"><strong>&nbsp;CDw60</strong></td>
<td bgcolor="#cccccc">&nbsp;</td>
<td bgcolor="#cccccc">&nbsp;9-O-acetyl-GD3; carbohydrate modification found on some gangliosides</td> <td bgcolor="#cccccc">&nbsp;Subset of T cells, platelets, thymic epithelium, activated keratinocytes,&nbsp;synovial fibroblasts, glomeruli, smooth muscle cells, astrocytes&nbsp;</td> <td bgcolor="#cccccc">&nbsp;Possible contributor to co-stimulatory/comitogenic signals for T cells&nbsp;</td>
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