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<td><strong> CD18</strong></td>
<td> 95</td> <td> β2 integrin chain; β subunit that combines with CD11a, CD11b, or CD11c subunit to form integrins</td> <td> All leukocytes </td> <td> Adhesion and signaling in the hematopoietic system (see entries for CD11a, CD11b, and CD11c) </td>
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<td bgcolor="#cccccc"><strong> CD19</strong></td>
<td bgcolor="#cccccc"> >120</td> <td bgcolor="#cccccc"> B4 </td> <td bgcolor="#cccccc"> Follicular dendritic cells, B cells from earliest recognizable B-lineage cells during development to B-cell blasts but lost on maturation to plasma cells </td> <td bgcolor="#cccccc"> Part of B-cell coreceptor with CD21 and CD81; a critical signal transduction molecule that regulates B-cell development, activation, and differentiation</td>
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<td><strong> CD20</strong></td>
<td> 33</td> <td> B1, Bp35 </td> <td> B cells </td> <td> Not known </td>
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<td bgcolor="#cccccc"><strong> CD21</strong></td>
<td bgcolor="#cccccc"> 145 (membrane form)<br /> 130 (soluble form)</td> <td bgcolor="#cccccc"> C3d receptor, CR2, Epstein Barr virus receptor (EBV-R) </td> <td bgcolor="#cccccc"> B cells, follicular dendritic cells, subset of immature thymocytes </td> <td bgcolor="#cccccc"> Receptor for EBV, C3d, C3dg, and iC3b; with CD19 and CD81, part of the B-cell coreceptor, a large signal-transduction complex </td>
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<td><strong> CD22</strong></td>
<td> 140</td> <td> BL-CAM, Lyb8 in mouse</td> <td> Surface of mature B cells, cytoplasm of late pro-and early pre-B cells </td> <td> Adhesion molecule; signaling molecule </td>
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<td bgcolor="#cccccc"><strong> CD23</strong></td>
<td bgcolor="#cccccc"> 45</td> <td bgcolor="#cccccc"> B6, BLAST-2, FcεRⅡ, Leu-20 ; low-affinity IgE receptor </td> <td bgcolor="#cccccc"> Human B cells, monocytes follicular dendritic cells </td> <td bgcolor="#cccccc"> Regulation of IgE synthesis; trigger to release TNF, IL-1, IL-6, and GM-CSF from human monocytes </td>
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<td><strong> CD24</strong></td>
<td> 35-45</td> <td> BA-1, heat-stable antigen (HSA) in mouse </td> <td> B-cell lineage but lost at plasma-cell stage, mature granulocytes </td> <td> Not known </td>
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<td bgcolor="#cccccc"><strong> CD25</strong></td>
<td bgcolor="#cccccc"> 55</td> <td bgcolor="#cccccc"> IL-2 receptor α chain, IL-2R, Tac antogen </td> <td bgcolor="#cccccc"> PHA-stimulated T cells; anti-IGM-stimulated B cells, LPS-stimulated monocytes/macrophages </td> <td bgcolor="#cccccc"> α subunit of receptor for cytokine IL-2 </td>
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<td><strong> CD26</strong></td>
<td> 110, 120</td> <td> EC 3.4.14.5, adenosine deaminase-binding protein (ADA-binding protein), dipeptidylpeptidase Ⅳ (DPV Ⅳ ectoenzyme) </td> <td> Mature of activated T cells, B cells, NK cells, macrophages</td> <td> Co-stimulatory molecule in T-cell activation </td>
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<td bgcolor="#cccccc"><strong> CD11bCD27</strong></td> <td bgcolor="#cccccc"> 55</td> <td bgcolor="#cccccc"> SI52, T14 </td> <td bgcolor="#cccccc"> Mature thymocytes, activated T cells and B cells, NK cells, macrophages, most peropheral T cells, memory-type B cells </td> <td bgcolor="#cccccc"> Mediation of a co-stimulatory signal for T- and B-cell activation; role in murine T-cell development </td>
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<td><strong> CD27CD28</strong></td> <td> 90 (homodimeric form)</td> <td> T44, Tp44 </td> <td> Matur CD3+ thymocytes, most peripheral T cells, plasma cells </td> <td> Co-stimulation of T-cell proliferation and cytokine production upon binding CD80 or CD86 </td>
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<td bgcolor="#cccccc"><strong> CD28CD29</strong></td> <td bgcolor="#cccccc"> 130</td> <td bgcolor="#cccccc"> β1 integrin chain, GP, platelet GPⅡa, VLA-β chain </td> <td bgcolor="#cccccc"> Leukocytes </td> <td bgcolor="#cccccc"> β subunit of VLA-1 integrin </td>
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<td><strong> CD29CD30</strong></td> <td> 120</td> <td> </td> <td>Ber-H2 antigen, Ki-1 antigen </td> <td> </td> </tr> <tr> <td bgcolor="#cccccc">Activated T cells, activated B cells, activated NK cells, monocytes <strong>CD30</strong></td> <td bgcolor="#cccccc"> </td> <td bgcolor="#cccccc"> </td> <td bgcolor="#cccccc"> </td> <td bgcolor="#cccccc">Stimulation of proliferation or induction of cell death, depending upon conditions and cell type expressing it </td>
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