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CBL mediated ligand-induced downregulation of EGF receptor

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<a href="http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_cblPathway.gif">http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_cblPathway.gif</a>&nbsp;<br /><br /><table style="WIDTH: 722px; HEIGHT: 243px" cellspacing="1" cellpadding="1" width="722" align="center" summary="" border="1"> <tbody> <tr> <td>&nbsp;</td> <td>&nbsp;</td> </tr> <tr> <td> <p align="center">EGF</p> </td> <td> <p align="center">EGF R</p> </td> </tr> <tr> <td> <p align="center">EGF R</p> </td> <td> <p align="center">EGF</p> </td> </tr> <tr> <td> <p align="center">EGF R</p> </td> <td> <p align="center">PKC</p> </td> </tr> <tr> <td> <p align="center">EGF R</p> </td> <td> <p align="center">Grb2</p> </td> </tr> <tr> <td> <p align="center">EGF R</p> </td> <td> <p align="center">Ub</p> </td> </tr> <tr> <td> <p align="center">GRB2</p> </td> <td> <p align="center">CBL</p> </td> </tr> <tr> <td> <p align="center">GRB2</p> </td> <td> <p align="center">END</p> </td> </tr> <tr> <td> <p align="center">GRB2</p> </td> <td> <p align="center">EGF R</p> </td> </tr> <tr> <td> <p align="center">PKC</p> </td> <td> <p align="center">EGF R</p> </td> </tr> <tr> <td> <p align="center">CBL</p> </td> <td> <p align="center">Grb2</p> </td> </tr> <tr> <td> <p align="center">CBL</p> </td> <td> <p align="center">END</p> </td> </tr> </tbody></table>

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