Fc Epsilon Receptor Ⅰ signaling in Mast Cells
From Opengenome.net
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|
|
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BTK |
LYN |
|
BTK |
PI3K |
|
BTK |
PLCr |
|
BTK |
RAS |
|
SYK |
VAV |
|
SYK |
SHC |
|
SYK |
LYN |
|
VAV |
GTP |
|
VAV |
RAS |
|
VAV |
SYK |
|
RAF1 |
RAS-GTP |
|
RAF1 |
MEK1 |
|
SHC1 |
GRB2 |
|
SHC1 |
SYK |
|
SOS1 |
GRB2 |
|
SOS1 |
GTP |
|
SOS1 |
PI3K |
|
NFATC1 |
CALCINEURIN-CaM |
|
FOS |
ELK1 |
|
ELK1 |
C-FOS Complex |
|
ELK1 |
ERK1-ERK2 Complex |
|
PLA2G6 |
ERK1-ERK2 |
|
PLA2G6 |
Arachidonic Acid Release |
|
PIK3CB |
SHC-GRB2-SOS1 Complex |
|
PIK3CB |
RAS-GTP Complex |
|
LYN |
BTK |
|
LYN |
PI3K |
|
LYN |
SYK |
|
JUN |
JNK1 |
|
PAK2 |
MEKK1 |
|
PAK2 |
RAS |
|
GRB2 |
SHC |
|
GRB2 |
SOS-1 |
|
GRB2 |
GTP |
TRANSCRIPTION FACTOR
=NFATc, C-JUN, C-FOS, ELK-1
