Eph Kinases and ephrins Support platelet aggregation
From Opengenome.net
http://cgap.nci.nih.gov/BIOCARTA/Pathways/h_ephA4Pathway.gif
RAP1B |
Integrin-b--Integrin-a--Fibrinogen Complex |
RAP1B |
EphrinB1-Sfk?-EphA4 Complex |
LYN |
FYN |
LYN |
EphA1 |
LYN |
GPCR |
L1CAM |
Integrin-a |
L1CAM |
L1CAM |
L1CAM |
? |
FYN |
LYN |
FYN |
EphA4 |
FYN |
ACTIN |
FYN |
Secretion |
ITGB1 |
Fibrinogen |
ITGB1 |
Integrin-a |
EprlA4 |
FYN |
EprlA4 |
LYN |
EprlA4 |
? |
EprlA4 |
ephrinB1 |
EPHB1 |
Sfk? |
EPHB1 |
Epha4 |
EPHB1 |
RAP1B |