ER-associated degradation(ERAD) Pathway
From Opengenome.net
cANX |
Glc1 Man9 |
cANX |
EDEM |
FBX2 |
SKP1 |
FBX2 |
ROC1 |
VGCGL1 |
Man9 |
CUL |
SKP1 |
CUL |
ROC1 |
CUL |
E2 |
CUL |
E1 |
EDEM |
Man8 |
EDEM |
CNX |
EDEM |
Glc1 Man8 |
MAN2A2 |
Folded protein |
MAN2A2 |
Man8-7 |
SKP1A |
FBX2 |
SKP1A |
CUL1 |
UBE2I |
CUL1 |
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