Cdc25 and chk1 Regulatory Pathway in Response to DNA damage
From Opengenome.net
http://cgap.nci.nih.gov/BIOCARTA/Pathways/H_cdc25Pathway.gif
|
CDC2 |
CDC25 |
|
CDC2 |
WEE1 |
|
CDC2 |
MYT1 |
|
CDC2 |
Mitotic cycle |
|
CHEK1 |
ATM |
|
CHEK1 |
CDC25 |
|
WEE1 |
CDC2 |
|
MYT |
CDC2-Tyr15 phosphorylation |
|
MYT |
CDC2-Thr14 phosphorylation |
|
ATM |
Damage DNA |
|
ATM |
CHK1 |
